Ebola Virus Ribonucleic Acid Detection in Semen More Than Two Years After Resolution of Acute Ebola Virus Infection
Author(s) -
William A. Fischer,
Jerry Brown,
David A. Wohl,
Amy James Loftis,
Sam Tozay,
Edwina Reeves,
Korto Pewu,
Galapaki Gorvego,
Saturday Quellie,
Coleen K. Cunningham,
Carson Merenbloom,
Sonia Napravnik,
Karine Dubé,
David Adjasoo,
Erin H. Jones,
Korlia Bonarwolo,
David L. Hoover
Publication year - 2017
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofx155
Subject(s) - ebola virus , semen , virology , medicine , rna , virus , vp40 , ebolavirus , biology , andrology , gene , biochemistry
Among 149 men who survived Ebola virus disease (EVD) and donated semen 260-1016 days after EVD onset, Ebola virus (EBOV) ribonucleic acid (RNA) was detected in 13 (9%). Of 137 men who donated semen 2 years after EVD onset, 11 (8%) had an EBOV RNA-positive specimen. The mechanism underlying the persistence of EBOV RNA in semen is unclear, and it is unclear whether the detection of viral RNA represents the presence of infectious virus.
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