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Detection of mcr-1-Carrying Escherichia coli Causing Bloodstream Infection in a New York City Hospital: Avian Origins, Human Concerns?
Author(s) -
Nenad Macesic,
Daniel Green,
Zheng Wang,
Sean B. Sullivan,
Kevin G. Shim,
Sarah Park,
Susan Whittier,
E. Yoko Furuya,
Angela GomezSimmonds,
AnneCatrin Uhlemann
Publication year - 2017
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofx115
Subject(s) - medicine , escherichia coli , bloodstream infection , microbiology and biotechnology , virology , intensive care medicine , biology , genetics , gene
The spread of mcr-1 in the United States remains poorly defined. mcr-1-producing Escherichia coli that also carried blaSHV-12 was detected in a hospitalized patient. No additional cases were identified during screening of 801 Gram-negative isolates. Genomic sequencing identified an IncX4 mcr-1- harboring plasmid and ST117 clonal background associated with avian pathogenic E coli.

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