Risk Factors Associated With Outpatient Parenteral Antibiotic Therapy Program Failure Among Intravenous Drug Users | Zendy

Deanna J. Buehrle | Zendy; Ryan K. Shields | Zendy; Neel Shah | Zendy; Christopher Shoff | Zendy; Kathleen Sheridan | Zendy

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Risk Factors Associated With Outpatient Parenteral Antibiotic Therapy Program Failure Among Intravenous Drug Users

Author(s) -

Deanna J. Buehrle,

Ryan K. Shields,

Neel Shah,

Christopher Shoff,

Kathleen Sheridan

Publication year - 2017

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofx102

Subject(s) - medicine , intravenous drug , drug , intensive care medicine , antibiotics , intravenous antibiotics , emergency medicine , pharmacology , family medicine , human immunodeficiency virus (hiv) , viral disease , microbiology and biotechnology , biology

Sixty-one percent of intravenous drug users (IVDUs) who received outpatient parenteral antibiotic therapy (OPAT) failed treatment. Hospital readmission and adverse drug reactions occurred in 25%. By multivariate analysis, time since last IVDU was associated with failure (P = .04). Intravenous drug users requiring OPAT are at high risk for failure; additional studies are needed to explore alternatives.

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