Decreased Microvascular Function in Tanzanian Children With Severe and Uncomplicated Falciparum Malaria | Zendy

Tsin Wen Yeo | Zendy; Salvatore M. Florence | Zendy; Ayam R. Kalingonji | Zendy; Youwei Chen | Zendy; Donald L. Granger | Zendy; Nicholas M. Anstey | Zendy; Esther D. Mwaikambo | Zendy; J. Brice Weinberg | Zendy

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Decreased Microvascular Function in Tanzanian Children With Severe and Uncomplicated Falciparum Malaria

Author(s) -

Tsin Wen Yeo,

Salvatore M. Florence,

Ayam R. Kalingonji,

Youwei Chen,

Donald L. Granger,

Nicholas M. Anstey,

Esther D. Mwaikambo,

J. Brice Weinberg

Publication year - 2017

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofx079

Subject(s) - malaria , medicine , plasmodium falciparum , oxygen , physiology , immunology , chemistry , organic chemistry

Microvascular function and oxygen consumption affect oxygen homeostasis but have not been assessed in African children with malaria. Microvascular function in Tanzanian children with severe malaria (SM) or uncomplicated malaria were 39% and 72%, respectively, of controls (P < .001). Uncomplicated malaria (P = .04), not SM (P = .06), children had increased oxygen consumption compared with controls.

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