Influence of Antibiotics on the Detection of Bacteria by Culture-Based and Culture-Independent Diagnostic Tests in Patients Hospitalized With Community-Acquired Pneumonia
Author(s) -
Aaron M. Harris,
Anna M. Bramley,
Seema Jain,
Sandra R. Arnold,
Krow Ampofo,
Wesley H. Self,
Derek J. Williams,
Evan J. Anderson,
Carlos G. Grijalva,
Jonathan A. McCullers,
Andrew T. Pavia,
Richard G. Wunderink,
Kathryn M. Edwards,
Jonas M. Winchell,
Lauri A. Hicks
Publication year - 2017
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofx014
Subject(s) - medicine , antibiotics , sputum , pneumonia , microbiological culture , sputum culture , blood culture , streptococcus pneumoniae , bacterial pneumonia , mycoplasma pneumoniae , microbiology and biotechnology , bacteria , pathology , tuberculosis , biology , genetics
Bacteria were less frequently detected in culture-based tests collected after antibiotics and in culture-independent tests that had longer intervals between antibiotic exposure and specimen collection. Bacterial yield could improve if specimens were collected promptly, preferably before antibiotics, providing data for improved antibiotic selection.
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