Characteristics and Mortality of Pneumocystis Pneumonia in Patients With Cushing’s Syndrome: A Plea for Timely Initiation of Chemoprophylaxis | Zendy

Karlijn van Halem | Zendy; Lucia Vrolijk | Zendy; Alberto M. Pereira | Zendy; Mark de Boer | Zendy

Open Access

Characteristics and Mortality of Pneumocystis Pneumonia in Patients With Cushing’s Syndrome: A Plea for Timely Initiation of Chemoprophylaxis

Author(s) -

Karlijn van Halem,

Lucia Vrolijk,

Alberto M. Pereira,

Mark de Boer

Publication year - 2017

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofx002

Subject(s) - medicine , plea , chemoprophylaxis , pneumonia , intensive care medicine , pediatrics , law , political science

In patients with Cushing's syndrome, development of pneumonia (PCP) is associated with extreme cortisol production levels. In this setting, immune reconstitution after abrogation of cortisol excess appears to induce development of symptomatic PCP. The high mortality rate warrants timely initiation of chemoprophylaxis or even preemptive treatment of PCP.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research