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Cost Effectiveness and Cost Containment in the Era of Interferon-Free Therapies to Treat Hepatitis C Virus Genotype 1
Author(s) -
Benjamin P. Linas,
Jake R. Morgan,
Mai T. Pho,
Jared A. Leff,
Bruce R. Schackman,
C. Robert Horsburgh,
Sabrina A. Assoumou,
Joshua A. Salomon,
Milton C. Weinstein,
Kenneth A. Freedberg,
Arthur Y. Kim
Publication year - 2016
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofw266
Subject(s) - medicine , regimen , cost effectiveness , hepatitis c , intensive care medicine , risk analysis (engineering)
Treatment strategies using interferon-free therapies to treat all HCV-infected persons are cost effective, but short-term cost is high. Among noncirrhotic patients, using the least costly interferon-free regimen, even if it is not single tablet or once daily, is the cost-control strategy that results in best outcomes. Restricting treatment to patients with more advanced disease often results in worse outcomes than treating all patients, and it is not preferred.

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