Colonization With Vancomycin-Resistant Enterococci and Risk for Bloodstream Infection Among Patients With Malignancy: A Systematic Review and Meta-Analysis
Author(s) -
Michail Alevizakos,
Apostolos Gaitanidis,
Dimitrios Nasioudis,
Katerina Tori,
Myrto Eleni Flokas,
Eleftherios Mylonakis
Publication year - 2016
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofw246
Subject(s) - medicine , bloodstream infection , gram positive bacterial infections , vancomycin resistant enterococci , colonization , vancomycin , malignancy , enterococcus , microbiology and biotechnology , meta analysis , intensive care medicine , antibiotics , staphylococcus aureus , bacteria , biology , genetics
A substantial VRE colonization burden exists among patients with malignancy, and colonization greatly increases the risk for subsequent VRE bloodstream infection. Adherence to antimicrobial stewardship is needed, and a re-evaluation of the use of vancomycin as empiric therapy in this patient population may be warranted.
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