Elevated Voriconazole Level Associated With Hallucinations and Suicidal Ideation: A Case Report | Zendy

Jeffrey W. Jansen | Zendy; Sumon K. Sen | Zendy; Ryan P Moenster | Zendy

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Elevated Voriconazole Level Associated With Hallucinations and Suicidal Ideation: A Case Report

Author(s) -

Jeffrey W. Jansen,

Sumon K. Sen,

Ryan P Moenster

Publication year - 2017

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofw215

Subject(s) - voriconazole , medicine , visual hallucination , suicidal ideation , aspergillosis , antifungal , cyp2c19 , psychiatry , dermatology , poison control , emergency medicine , injury prevention , immunology , cytochrome p450 , metabolism

Voriconazole, a broad-spectrum antifungal, has been associated with visual and auditory hallucinations. We report the case of patient being treated with voriconazole for pulmonary aspergillosis who developed visual hallucinations and new suicidal ideation with plan. Voriconazole troughs were supratherapeutic (9.0 mcg/mL) and the patient was positive for the CYP2C19*1/*2 allele.

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