A Quaternary Ammonium Disinfectant Containing Germinants Reduces Clostridium difficile Spores on Surfaces by Inducing Susceptibility to Environmental Stressors | Zendy

Michelle M. Nerandzic | Zendy; Curtis J. Donskey | Zendy

Open Access

A Quaternary Ammonium Disinfectant Containing Germinants Reduces Clostridium difficile Spores on Surfaces by Inducing Susceptibility to Environmental Stressors

Author(s) -

Michelle M. Nerandzic,

Curtis J. Donskey

Publication year - 2016

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofw196

Subject(s) - spore , disinfectant , clostridium difficile , ammonium , microbiology and biotechnology , endospore , medicine , contamination , clostridium , bacteria , chemistry , biology , antibiotics , ecology , organic chemistry , genetics , pathology

Exposing Clostridium difficile spores to germinants in a quaternary ammonium matrix was an effective method to reduce environmental contamination by sensitizing the spores, leaving them susceptible to ambient conditions and enhancing killing by acid, high-intensity visible light, and radiation.

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