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Streptococcus pneumoniae Nasopharyngeal Carriage Rates, Serotype Distribution and Vaccine Effectiveness in Vaccinated and Non-vaccinated Healthy Children in Guatemala City
Author(s) -
Mario Melgar,
Isabel Hernández Pérez,
Rene Ordoñez,
Irwin Paniagua,
Claudia Vargas
Publication year - 2016
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofw172.638
Subject(s) - medicine , carriage , serotype , streptococcus pneumoniae , virology , vaccination , pediatrics , microbiology and biotechnology , antibiotics , biology , pathology
BACKGROUND • Streptococcus pneumoniae (Spn) vaccines have different efficacy rate according to setting • Assuming colonization as a surrogate for vaccine efficacy. • Study looked for Spn nasopharyngeal carriage in: • vaccinated and non vaccinated • healthy children under 5 years of age • From public and private clinics • Conjugated pneumococcal conjugated vaccine (PCV) was available only in private practice

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