Deciphering the Effects of Injectable Pre-exposure Prophylaxis for Combination Human Immunodeficiency Virus Prevention
Author(s) -
Robert Glaubius,
Urvi M. Parikh,
Greg Hood,
Kerri J. Penrose,
Eran Bendavid,
John W. Mellors,
Ume L. Abbas
Publication year - 2016
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofw125
Subject(s) - pre exposure prophylaxis , medicine , drug resistance , rilpivirine , human immunodeficiency virus (hiv) , antiretroviral therapy , virology , viral load , men who have sex with men , biology , syphilis , microbiology and biotechnology
Injectable antiretrovirals including non-nucleoside reverse transcriptase inhibitors are being evaluated for pre-exposure prophylaxis for HIV prevention. Mathematical modeling suggests that injectable pre-exposure prophylaxis among KwaZulu-Natal's at-risk populations could have substantial preventive impact but may increase drug resistance unless highly effective.
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