A Novel Shiga Toxin 1a-Converting Bacteriophage of Shigella sonnei With Close Relationship to Shiga Toxin 2-Converting Pages of Escherichia coli | Zendy

Christoph C Carter | Zendy; Joshua Fierer | Zendy; Wei Wei Chiu | Zendy; David J. Looney | Zendy; Matthew C. Strain | Zendy; Sanjay R. Mehta | Zendy

Open Access

A Novel Shiga Toxin 1a-Converting Bacteriophage of Shigella sonnei With Close Relationship to Shiga Toxin 2-Converting Pages of Escherichia coli

Author(s) -

Christoph C Carter,

Joshua Fierer,

Wei Wei Chiu,

David J. Looney,

Matthew C. Strain,

Sanjay R. Mehta

Publication year - 2016

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofw079

Subject(s) - shiga toxin , shigella dysenteriae , shigella sonnei , shigella , microbiology and biotechnology , escherichia coli , bacteriophage , toxin , virology , biology , escherichia , genetics , gene

In recent studies, strains of non-dysenteriae 1 Shigella (NDS) expressing Shiga toxin have been reported. In this study, we report a novel stx1a-converting bacteriophage of Shigella sonnei associated with travel to Mexico. Phylogenetic comparison between this and other stx-converting phages suggests that toxigenic NDS strains have arisen through separate horizontal transfer events from toxigenic Escherichia coli.

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