Open AccessA Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis
Author(s) -
Michael S. Abers,
Musie Ghebremichael,
Allison K. Timmons,
H. Shaw Warren,
Mark C. Poznansky,
Jatin M. Vyas
Publication year - 2016
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofw036
Subject(s) - neutropenia , medicine , aspergillosis , intensive care medicine , risk factor , immunology , toxicity
Prolonged neutropenia is generally thought to be the major factor for invasive pulmonary aspergillosis (IPA). In the present study, we characterize the frequency, severity, and duration of neutropenia that immediately precedes IPA. Prolonged neutropenia was identified in only one third of all IPA cases and occurred exclusively in hematologic patients.
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