Miltefosine for Mucosal and Complicated Cutaneous Old World Leishmaniasis: A Case Series and Review of the Literature
Author(s) -
Vincent Mosimann,
C. Blazek,
Heini Grob,
Matthew Chaney,
Andreas Neumayr,
Johannes Blum
Publication year - 2016
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofw008
Subject(s) - miltefosine , medicine , leishmaniasis , dermatology , cutaneous leishmaniasis , series (stratigraphy) , visceral leishmaniasis , pathology , paleontology , biology
Complicated Old World cutaneous leishmaniasis (OWCL) and Old World mucosal leishmaniasis (OWML) constitute an indication for systemic treatment. To date, there no controlled clinical studies that compare treatment options for these diseases. We compiled a case series of 24 cases successfully treated with miltefosine. We conclude that oral miltefosine is an effective treatment option for both OWCL and OWML.
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