Completion Rate and Side-Effect Profile of Three-Month Isoniazid and Rifapentine Treatment for Latent Tuberculosis Infection in an Urban County Jail
Author(s) -
María Juarez-Reyes,
Mark Gallivan,
Alexander Chyorny,
Linda M. O’Keeffe,
Neha Shah
Publication year - 2016
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofv220
Subject(s) - rifapentine , medicine , latent tuberculosis , isoniazid , tuberculosis , spec# , pharmacology , mycobacterium tuberculosis , pathology , computer science , programming language
In an urban jail population, 3 months of isoniazid and rifapentine (3HP) was associated with an 85% latent tuberculosis infection treatment completion rate compared with 18% in a standard 9-month isoniazid treatment group. Among the 91 patients who started 3HP therapy, there were 2 treatment discontinuations from adverse drug reactions.
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