Chronic Q-Fever (Coxiella burnetii) Causing Abdominal Aortic Aneurysm and Lumbar Osteomyelitis: A Case Report | Zendy

P. Alexander Leahey | Zendy; Steven R. Tahan | Zendy; Ekkehard M. Kasper | Zendy; Mary Albrecht | Zendy

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Chronic Q-Fever (Coxiella burnetii) Causing Abdominal Aortic Aneurysm and Lumbar Osteomyelitis: A Case Report

Author(s) -

P. Alexander Leahey,

Steven R. Tahan,

Ekkehard M. Kasper,

Mary Albrecht

Publication year - 2015

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofv185

Subject(s) - medicine , coxiella burnetii , q fever , vertebral osteomyelitis , osteomyelitis , abdominal aortic aneurysm , lumbar , radiology , aneurysm , aortic aneurysm , surgery , virology

Coxiella burnetii is a rare cause of chronic infection that most frequently presents as endocarditis. We report a case of C burnetii causing an infected abdominal aortic aneurysm with contiguous lumbar osteomyelitis resulting in spinal cord compromise. The diagnosis was established by serologic studies consistent with chronic Q-fever (ratio of C burnetii immunoglobulin [Ig]G phase II titer to IgG phase I titer <1) and was confirmed by positive C burnetii polymerase chain reaction of vertebral tissue in addition to pathology of vertebral bone showing intracellular Gram-negative coccobacillary bacteria. The patient clinically improved after surgical decompression and prolonged treatment with doxycycline and hydroxychloroquine.

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