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Primary Larynx Cryptococcus neoformans Infection: A Distinctive Clinical Entity
Author(s) -
Mathieu Bergeron,
Andrée-Anne Gagné,
Mathieu Côté,
Jacinthe Chênevert,
Robert Dubé,
René Pelletier
Publication year - 2015
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofv160
Subject(s) - cryptococcus neoformans , medicine , larynx , cryptococcus , fluconazole , cryptococcosis , biopsy , antifungal , dermatology , pathology , microbiology and biotechnology , surgery , biology
Cryptococcus neoformans can directly infect the vocal cords. Endoscopic findings were undistinctive from most infiltrative diseases. Tissue biopsy was essential for the diagnosis. Inhaled corticosteroids can predispose to the infection, and fluconazole 400 mg daily for at least 6 weeks appeared to be minimal to achieve a permanent cure.

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