Open AccessFCGR2A and FCGR3A Genotypes in Human Immunodeficiency Virus Mother-to-Child Transmission
Author(s) -
Caitlin Milligan,
Barbra A. Richardson,
Grace JohnStewart,
Ruth Nduati,
Julie Overbaugh
Publication year - 2015
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofv149
Subject(s) - medicine , genotype , immunology , breastfeeding , transmission (telecommunications) , cohort , virology , biology , pediatrics , genetics , gene , electrical engineering , engineering
Host FcγR polymorphisms may influence HIV infection and disease progression. Here, we examine FCGR2A and FCGR3A genotypes in HIV mother-to-child transmission. Infant genotypes did not impact infection or progression, but the maternal FCGR3A genotype may influence early breastfeeding transmission risk.
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