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Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report
Author(s) -
Ahmad Salameh,
Nancy Bello,
Jennifer Becker,
Tirdad T. Zangeneh
Publication year - 2015
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofv104
Subject(s) - medicine , miltefosine , acanthamoeba , azithromycin , flucytosine , meningoencephalitis , naegleria fowleri , fluconazole , pentamidine , sulfadiazine , encephalitis , meningitis , immunology , dermatology , leishmaniasis , microbiology and biotechnology , pneumonia , antifungal , surgery , antibiotics , virus , visceral leishmaniasis , biology
Granulomatous amoebic encephalitis (GAE) due to Acanthamoeba is almost a uniformly fatal infection in immune-compromised hosts despite multidrug combination therapy. We report a case of GAE in a female who received a deceased donor kidney graft. She was treated with a combination of miltefosine, pentamidine, sulfadiazine, fluconazole, flucytosine, and azithromycin.

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