Impact of Late Oseltamivir Treatment on Influenza Symptoms in the Outpatient Setting: Results of a Randomized Trial | Zendy

Huong Q. McLean | Zendy; Edward A. Belongia | Zendy; Burney A. Kieke | Zendy; Jennifer K. Meece | Zendy; Alicia M. Fry | Zendy

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Impact of Late Oseltamivir Treatment on Influenza Symptoms in the Outpatient Setting: Results of a Randomized Trial

Author(s) -

Huong Q. McLean,

Edward A. Belongia,

Burney A. Kieke,

Jennifer K. Meece,

Alicia M. Fry

Publication year - 2015

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofv100

Subject(s) - oseltamivir , medicine , randomized controlled trial , influenza like illness , pediatrics , emergency medicine , physical therapy , virology , virus , covid-19 , disease , infectious disease (medical specialty)

We conducted a double-blind, randomized trial of 134 outpatients with polymerase chain reaction-confirmed influenza to assess the effects of oseltamivir initiated 48-119 hours after illness onset. Oseltamivir treatment did not reduce illness duration, severity, or duration of virus detection. However, the power of this study was limited due to lower than expected enrollment.

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