Loss of Vancomycin-Resistant Enterococcus Fecal Dominance in an Organ Transplant Patient With Clostridium difficile Colitis After Fecal Microbiota Transplant | Zendy

Joshua Stripling | Zendy; Ranjit Kumar | Zendy; John W. Baddley | Zendy; Anoma Nellore | Zendy; Paula Dixon | Zendy; Donna Howard | Zendy; Travis Ptacek | Zendy; Elliot J. Lefkowitz | Zendy; José Tallaj | Zendy; William H. Benjamin | Zendy; Casey D. Morrow | Zendy; J. Martín Rodríguez | Zendy

Open Access

Loss of Vancomycin-Resistant Enterococcus Fecal Dominance in an Organ Transplant Patient With Clostridium difficile Colitis After Fecal Microbiota Transplant

Author(s) -

Joshua Stripling,

Ranjit Kumar,

John W. Baddley,

Anoma Nellore,

Paula Dixon,

Donna Howard,

Travis Ptacek,

Elliot J. Lefkowitz,

José Tallaj,

William H. Benjamin,

Casey D. Morrow,

J. Martín Rodríguez

Publication year - 2015

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofv078

Subject(s) - clostridium difficile , medicine , clostridium difficile colitis , fecal bacteriotherapy , vancomycin resistant enterococcus , feces , enterococcus , vancomycin , colitis , diarrhea , microbiology and biotechnology , antibiotics , biology , bacteria , staphylococcus aureus , genetics

We report the use of fecal microbiota transplantation in a single heart-kidney transplant recipient with recurrent Clostridium difficile, vancomycin-resistant Enterococcus (VRE) fecal dominance, and recurrent VRE infections. Fecal microbiota transplantation resulted in the reconstruction of a diverse microbiota with (1) reduced relative abundance of C difficile and VRE and (2) positive clinical outcome.

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