Risk Factors for Developing Active Tuberculosis After the Treatment of Latent Tuberculosis in Adults Infected With Human Immunodeficiency Virus
Author(s) -
Kojo Amoakwa,
Neil Martinson,
Lawrence H. Moulton,
Grace L. Barnes,
Reginah Msandiwa,
Richard E. Chaisson
Publication year - 2014
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofu120
Subject(s) - medicine , tuberculosis , latent tuberculosis , human immunodeficiency virus (hiv) , tuberculin , active tuberculosis , immunology , virology , mycobacterium tuberculosis , pathology
Tuberculosis is the leading cause of death among adults infected with human immunodeficiency virus (HIV), and rates of tuberculosis remain high even after preventive therapy. Among 908 HIV-infected adults in a trial of preventive treatment, we found self-reported alcohol consumption, low baseline CD4 count, high baseline viral load, and tuberculin skin test size >15 mm as independent risk factors for incident tuberculosis.
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