Ceftaroline in Combination With Trimethoprim-Sulfamethoxazole for Salvage Therapy of Methicillin-Resistant Staphylococcus aureus Bacteremia and Endocarditis | Zendy

Valeria Fabre | Zendy; Marcela A. Ferrada | Zendy; Whitney R. Buckel | Zendy; Edina Avdic | Zendy; Sara E. Cosgrove | Zendy

Open Access

Ceftaroline in Combination With Trimethoprim-Sulfamethoxazole for Salvage Therapy of Methicillin-Resistant Staphylococcus aureus Bacteremia and Endocarditis

Author(s) -

Valeria Fabre,

Marcela A. Ferrada,

Whitney R. Buckel,

Edina Avdic,

Sara E. Cosgrove

Publication year - 2014

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofu046

Subject(s) - medicine , bacteremia , endocarditis , methicillin resistant staphylococcus aureus , staphylococcus aureus , trimethoprim , antimicrobial , salvage therapy , sulfamethoxazole , osteomyelitis , staphylococcal infections , surgery , antibiotics , microbiology and biotechnology , chemotherapy , bacteria , genetics , biology

No clinical trials have investigated the use of ceftaroline fosamil for salvage therapy of methicillin-resistant Staphylococcus aureus bacteremia and endocarditis. We report data on 29 patients who received ceftaroline ± another antimicrobial for this indication. Ninety percent of patients had microbiologic cure and 31% had treatment success with a median follow-up of 6 months.

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