Modeling-Based Response-Guided DAA Therapy for Chronic Hepatitis C to Identify Individuals for Shortening Treatment Duration
Author(s) -
Ashish Goyal,
Alex Churkin,
Danny Barash,
Scott J. Cotler,
Amir Shlomai,
Ohad Etzion,
Harel Dahari
Publication year - 2022
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofac157
Subject(s) - medicine , chronic hepatitis , duration (music) , antiviral therapy , combination therapy , hepatitis c virus , intensive care medicine , virus , immunology , art , literature
Shortening duration of direct-acting antiviral therapy for chronic hepatitis C could provide cost savings, reduce medication exposure, and foster adherence and treatment completion in special populations. The current analysis indicates that measuring hepatitis C virus at baseline and on days 7 and 14 of therapy can identify patients for shortening therapy duration.
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