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Symptomatic Plasmodium vivax Infection in Rwanda
Author(s) -
Jessica N. McCaffery,
Tharcisse Munyaneza,
Aline Uwimana,
Doug Nace,
Naomi W. Lucchi,
Eric S. Halsey,
Eric Rogier
Publication year - 2022
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofac025
Subject(s) - plasmodium vivax , plasmodium falciparum , malaria , medicine , virology , artemether/lumefantrine , plasmodium (life cycle) , polymerase chain reaction , lactate dehydrogenase , immunology , biology , parasite hosting , enzyme , artemisinin , genetics , biochemistry , gene , world wide web , computer science
We report a Plasmodium vivax infection in a Rwandan child misdiagnosed with Plasmodium falciparum and administered artemether-lumefantrine. Antigen detection revealed an absence of P falciparum histidine-rich protein 2 (HRP2) and presence of Plasmodium vivax lactate dehydrogenase. Nested and real-time polymerase chain reactions verified that the sample only contained P vivax deoxyribonucleic acid.

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