Distribution of Aspergillus Species and Prevalence of Azole Resistance in Respiratory Samples From Swiss Tertiary Care Hospitals | Zendy

Silvio Ragozzino | Zendy; Daniel Goldenberger | Zendy; Patrick R. Wright | Zendy; Stefan Zimmerli | Zendy; Konrad Mühlethaler | Zendy; Dionysios Neofytos | Zendy; Arnaud Riat | Zendy; Katia Boggian | Zendy; Oliver Nolte | Zendy; Anna Conen | Zendy; Hans Fankhauser | Zendy; Peter W. Schreiber | Zendy; Reinhard Zbinden | Zendy; Frédéric Lamoth | Zendy; Nina Khanna | Zendy

Open Access

Distribution of Aspergillus Species and Prevalence of Azole Resistance in Respiratory Samples From Swiss Tertiary Care Hospitals

Author(s) -

Silvio Ragozzino,

Daniel Goldenberger,

Patrick R. Wright,

Stefan Zimmerli,

Konrad Mühlethaler,

Dionysios Neofytos,

Arnaud Riat,

Katia Boggian,

Oliver Nolte,

Anna Conen,

Hans Fankhauser,

Peter W. Schreiber,

Reinhard Zbinden,

Frédéric Lamoth,

Nina Khanna

Publication year - 2021

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofab638

Subject(s) - aspergillus fumigatus , azole , aspergillus , microbiology and biotechnology , medicine , respiratory system , aspergillosis , drug resistance , antifungal , biology , immunology

Among 400 Aspergillus species from respiratory samples in Switzerland, Aspergillus fumigatus was the most frequent species. Non-fumigatus Aspergillus spp were more prevalent among solid organ transplant recipients and after azole exposure. Azole resistance was detected in 4 A fumigatus isolates, 3 of them with the “environmental” mutation TR34/L98H in the cyp51A gene.

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