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Data from the National Inpatient Sample demonstrate that methicillin-resistant Staphylococcus aureus (MRSA)–related septicemia hospitalizations increased from 1.67 (95% CI, 1.63–1.72) to 1.94 (95% CI, 1.88–2.00; Ptrend &amp;lt; .001) discharges per 1000 hospitalizations between 2016 and 2019. Regionally, the trends were similar. Rates of MSSA-related septicemia and pneumonia hospitalizations also increased significantly over this time period.

Methicillin-Resistant and Methicillin-Sensitive Staphylococcus aureus Hospitalizations: National Inpatient Sample, 2016–2019