Mycobacterium Avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient with AIDS: Case Report and Review of the Literature | Zendy

Courtney LaneDonovan | Zendy; Emma Bainbridge | Zendy; John D. Szumowski | Zendy; Andrew D. Kerkhoff | Zendy; Michael J. Peluso | Zendy

Open Access

Mycobacterium Avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient with AIDS: Case Report and Review of the Literature

Author(s) -

Courtney LaneDonovan,

Emma Bainbridge,

John D. Szumowski,

Andrew D. Kerkhoff,

Michael J. Peluso

Publication year - 2021

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofab450

Subject(s) - medicine , mycobacterium avium complex , iris (biosensor) , lesion , mass/lesion , pathology , mycobacterium , immunology , tuberculosis , artificial intelligence , computer science , biometrics

A patient with advanced HIV/AIDS presented with a brain abscess. While brain biopsy culture and pathology were unrevealing, universal broad-range PCR (uPCR) demonstrated Mycobacterium avium complex (MAC). We review the clinicopathologic characteristics of MAC brain abscesses and highlight the effectiveness of uPCR as a diagnostic tool in partially-treated infections.

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