Aspergillus lentulus: An Under-recognized Cause of Antifungal Drug-Resistant Aspergillosis | Zendy

Saman Nematollahi | Zendy; Nitipong Permpalung | Zendy; Sean X. Zhang | Zendy; Megan Morales | Zendy; Kieren A. Marr | Zendy

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Aspergillus lentulus: An Under-recognized Cause of Antifungal Drug-Resistant Aspergillosis

Author(s) -

Saman Nematollahi,

Nitipong Permpalung,

Sean X. Zhang,

Megan Morales,

Kieren A. Marr

Publication year - 2021

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofab392

Subject(s) - aspergillus fumigatus , aspergillosis , azole , aspergillus , antifungal , medicine , antifungal drug , microbiology and biotechnology , drug resistance , drug , biology , immunology , pharmacology

Aspergillus lentulus is a drug-resistant species that is phenotypically similar to A. fumigatus. It was discovered as a cause of azole-breakthrough disease, consistent with in vitro resistance. Clinical labs can misidentify the species as fumigatus based on phenotypic typing. We describe 4 recent cases and provide a brief review.

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