Relapsed Babesia microti Infection Following Allogeneic Hematopoietic Cell Transplantation in a Patient With B-cell Acute Lymphoblastic Leukemia: Case Report and Review of the Literature | Zendy

Joshua Rosenblatt | Zendy; Annie Leung | Zendy; Emily Baneman | Zendy; Risa Fuller | Zendy; Sarah Taimur | Zendy; Alberto PanizMondolfi | Zendy; Adriana K. Malone | Zendy; Laura A. Kirkman | Zendy; Samantha E. Jacobs | Zendy

Open Access

Relapsed Babesia microti Infection Following Allogeneic Hematopoietic Cell Transplantation in a Patient With B-cell Acute Lymphoblastic Leukemia: Case Report and Review of the Literature

Author(s) -

Joshua Rosenblatt,

Annie Leung,

Emily Baneman,

Risa Fuller,

Sarah Taimur,

Alberto PanizMondolfi,

Adriana K. Malone,

Laura A. Kirkman,

Samantha E. Jacobs

Publication year - 2021

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofab323

Subject(s) - atovaquone , medicine , babesiosis , acute leukemia , leukemia , hematopoietic stem cell transplantation , transplantation , immunology , babesia , pneumonia , virology , malaria , plasmodium falciparum

A patient with relapsed/refractory B-cell acute lymphoblastic leukemia developed babesiosis before allogeneic hematopoietic cell transplantation while on atovaquone for Pneumocystis jirovecii pneumonia prophylaxis. Despite receiving a prolonged course of atovaquone and azithromycin until whole-blood Babesia microti DNA was no longer detected by polymerase chain reaction, her post-transplant course was complicated by relapsed babesiosis. We investigate the potential host and parasite characteristics causing relapsing/persistent infection.

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