Discontinuation Patterns and Cost Avoidance of a Pharmacist-Driven Methicillin-Resistant Staphylococcus aureus Nasal Polymerase Chain Reaction Testing Protocol for De-escalation of Empiric Vancomycin for Suspected Pneumonia | Zendy

Lina Meng | Zendy; Samaneh Pourali | Zendy; Matthew M. Hitchcock | Zendy; David Ha | Zendy; Emily Mui | Zendy; William Alegria | Zendy; Emily M. Fox | Zendy; Calvin Diep | Zendy; Rebecca Swayngim | Zendy; Amy Chang | Zendy; Niaz Banaei | Zendy; Stan Deresinski | Zendy; Marisa Holubar | Zendy

Open Access

Discontinuation Patterns and Cost Avoidance of a Pharmacist-Driven Methicillin-Resistant Staphylococcus aureus Nasal Polymerase Chain Reaction Testing Protocol for De-escalation of Empiric Vancomycin for Suspected Pneumonia

Author(s) -

Lina Meng,

Samaneh Pourali,

Matthew M. Hitchcock,

David Ha,

Emily Mui,

William Alegria,

Emily M. Fox,

Calvin Diep,

Rebecca Swayngim,

Amy Chang,

Niaz Banaei,

Stan Deresinski,

Marisa Holubar

Publication year - 2021

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofab099

Subject(s) - medicine , discontinuation , vancomycin , de escalation , methicillin resistant staphylococcus aureus , staphylococcus aureus , pharmacist , concordance , pneumonia , pharmacy , family medicine , bacteria , biology , genetics

A pharmacist-driven methicillin-resistant Staphylococcus aureus (MRSA) nasal polymerase chain reaction (PCR)-based testing protocol with a 70% acceptance rate for vancomycin discontinuation within 24 hours of negative results significantly reduced unnecessary vancomycin use with an estimated cost avoidance of $40 per vancomycin course. We found high concordance (141 of 147, 96%) of culture-based versus PCR-based MRSA nasal screening.

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