A Multicenter Evaluation of the US Prevalence and Regional Variation in Macrolide-Resistant S. pneumoniae in Ambulatory and Hospitalized Adult Patients in the United States | Zendy

Vikas Gupta | Zendy; Kalvin Yu | Zendy; Jennifer Schranz | Zendy; Steven P Gelone | Zendy

Open Access

A Multicenter Evaluation of the US Prevalence and Regional Variation in Macrolide-Resistant S. pneumoniae in Ambulatory and Hospitalized Adult Patients in the United States

Author(s) -

Vikas Gupta,

Kalvin Yu,

Jennifer Schranz,

Steven P Gelone

Publication year - 2021

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofab063

Subject(s) - medicine , streptococcus pneumoniae , ambulatory , emergency medicine , microbiology and biotechnology , antibiotics , biology

Macrolide resistance was found in 39.5% of 3626 nonduplicate Streptococcus pneumoniae isolates from adult ambulatory and inpatient settings at 329 US hospitals (2018–2019). Macrolide resistance was significantly higher for respiratory vs blood isolates and ambulatory vs inpatient settings. Despite geographic variation, S. pneumoniae macrolide resistance was >25% in most regions.

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