Plasma and Cerebrospinal Fluid Therapeutic Drug Monitoring of Ceftolozane and Tazobactam During Treatment of Multidrug-Resistant Pseudomonas aeruginosa Meningitis | Zendy

Erin K McCreary | Zendy; Karin Byers | Zendy; Carolyn Fernandes | Zendy; Ellen G Kline | Zendy; David P. Nicolau | Zendy; Ryan K. Shields | Zendy

Open Access

Plasma and Cerebrospinal Fluid Therapeutic Drug Monitoring of Ceftolozane and Tazobactam During Treatment of Multidrug-Resistant Pseudomonas aeruginosa Meningitis

Author(s) -

Erin K McCreary,

Karin Byers,

Carolyn Fernandes,

Ellen G Kline,

David P. Nicolau,

Ryan K. Shields

Publication year - 2020

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofaa549

Subject(s) - medicine , pseudomonas aeruginosa , cerebrospinal fluid , tazobactam , meningitis , therapeutic drug monitoring , multiple drug resistance , drug resistance , drug , microbiology and biotechnology , intensive care medicine , piperacillin , pharmacology , surgery , bacteria , biology , genetics

We report a case of multidrug-resistant Pseudomonas aeruginosa meningitis treated with ceftolozane-tazobactam with concomitant therapeutic drug monitoring of plasma and cerebral spinal fluid. The data suggest that ceftolozane-tazobactam may be an option for select central nervous system infections; however, treatment decisions should be interpreted on a case-by-case basis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research