Respiratory Syncytial Virus Infection: Its Propensity for Bacterial Coinfection and Related Mortality in Elderly Adults | Zendy

Raphaël Godefroy | Zendy; Audrey GiraudGatineau | Zendy; Marie-Thérèse Jimeno | Zendy; Sophie Edouard | Zendy; Line Meddeb | Zendy; Christine Zandotti | Zendy; Hervé Chaudet | Zendy; Philippe Colson | Zendy; Didier Raoult | Zendy; Nadim Cassir | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Respiratory Syncytial Virus Infection: Its Propensity for Bacterial Coinfection and Related Mortality in Elderly Adults

Author(s) -

Raphaël Godefroy,

Audrey GiraudGatineau,

Marie-Thérèse Jimeno,

Sophie Edouard,

Line Meddeb,

Christine Zandotti,

Hervé Chaudet,

Philippe Colson,

Didier Raoult,

Nadim Cassir

Publication year - 2020

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofaa546

Subject(s) - coinfection , medicine , respiratory system , virus , hazard ratio , virology , confidence interval

Respiratory syncytial virus (RSV) is an increasingly recognized cause of acute respiratory infection (ARI) in adults. We compared the crude in-hospital mortality of patients with RSV infection alone with that of patients with RSV–bacterial coinfection. Overall, 12 144 hospitalized patients with ARI were screened for RSV detection by polymerase chain reaction between February 2014 and April 2019. In total, 701 (5.8%) had a positive RSV result, including 85 (12.1%) with bacterial coinfection. RSV–bacterial coinfection was associated with an increase in crude in-hospital mortality in patients >65 years old (hazard ratio, 2.94; 95% CI, 1.30–6.60; P = .010). Optimized prevention and management strategies to reduce this burden are needed.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research