SARS-CoV-2 Viral Load on Admission Is Associated With 30-Day Mortality
Author(s) -
Andrew Bryan,
Susan L. Fink,
Meghan A. Gattuso,
Gregory Pepper,
Anu Chaudhary,
Mark H. Wener,
Chihiro Morishima,
Keith R. Jerome,
Patrick C. Mathias,
Alexander L. Greninger
Publication year - 2020
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofaa535
Subject(s) - medicine , viral load , covid-19 , virology , virus , outbreak , disease , infectious disease (medical specialty)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load on admission was associated with a significantly increased 30-day mortality (odds ratio [OR], 4.20; 95% CI, 1.62–10.86), and anti-SARS-CoV-2 nucleocapisid IgG seropositivity on admission trended toward a reduced 30-day mortality (OR, 0.43; 95% CI, 0.15–1.26). Reporting of quantitative SARS-CoV-2 viral load and serologic assays may offer prognostic clinical information.
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