Field Evaluation of Cholkit Rapid Diagnostic Test forVibrio Cholerae O1During a Cholera Outbreak in Malawi, 2018 | Zendy

Innocent Chibwe | Zendy; Watipaso Kasambara | Zendy; Mathews Kagoli | Zendy; Harry Milala | Zendy; Charity Gondwe | Zendy; Andrew S. Azman | Zendy

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Field Evaluation of Cholkit Rapid Diagnostic Test forVibrio Cholerae O1During a Cholera Outbreak in Malawi, 2018

Author(s) -

Innocent Chibwe,

Watipaso Kasambara,

Mathews Kagoli,

Harry Milala,

Charity Gondwe,

Andrew S. Azman

Publication year - 2020

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofaa493

Subject(s) - vibrio cholerae , cholera , outbreak , medicine , virology , test (biology) , microbiology and biotechnology , biology , ecology , bacteria , genetics

Rapid diagnostic tests (RDTs) for cholera are an important emerging tool for surveillance, yet the currently available tests have several limitations. We assess the performance of a new RDT, Cholkit, during a cholera outbreak in Malawi compared with culture and find a sensitivity of 93.0% (95% CI, 83.0%–98.1%) and a specificity of 95.7% (95% CI, 78.1%–100.0%).

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