Clostridioides (Clostridium) difficile Pacemaker Infection | Zendy

Anna Berkefeld | Zendy; Fabian K. Berger | Zendy; Barbara C. Gärtner | Zendy; Nina Wantia | Zendy; Anatol Prinzing | Zendy; KarlLudwig Laugwitz | Zendy; Dirk H. Busch | Zendy; Kathrin Rothe | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Clostridioides (Clostridium) difficile Pacemaker Infection

Author(s) -

Anna Berkefeld,

Fabian K. Berger,

Barbara C. Gärtner,

Nina Wantia,

Anatol Prinzing,

KarlLudwig Laugwitz,

Dirk H. Busch,

Kathrin Rothe

Publication year - 2020

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofaa487

Subject(s) - medicine , clostridium difficile , clostridioides , diarrhea , vancomycin , genotyping , bacteremia , asymptomatic , metronidazole , antibiotics , intensive care medicine , microbiology and biotechnology , genotype , bacteria , biochemistry , chemistry , genetics , gene , biology , staphylococcus aureus

Clostridioides difficile is the leading cause of antibiotic-associated nosocomial diarrhea, but extra-intestinal manifestations are rare. We describe the first documented case of bacteraemia with pacemaker pocket and lead infection with the toxigenic C. difficile ribotype 014 with a lack of abdominal symptoms. The patient underwent pacemaker extraction and treatment with intravenous and oral vancomycin. Genotyping and molecular subtyping revealed clonality between pacemaker and intestinal isolates. This case illustrates the risk of intravascular device infections due to C. difficile. Even asymptomatic C. difficile colonization might pose a risk for prosthetic material infection.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research