Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study | Zendy

Say Tat Ooi | Zendy; Purnima Parthasarathy | Zendy; Yi Lin | Zendy; Valliammai D O Nallakaruppan | Zendy; Shereen Jia Huey Ng | Zendy; T. Tan | Zendy; Serena Low | Zendy; Terence Tang | Zendy

Open Access

Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study

Author(s) -

Say Tat Ooi,

Purnima Parthasarathy,

Yi Lin,

Valliammai D O Nallakaruppan,

Shereen Jia Huey Ng,

T. Tan,

Serena Low,

Terence Tang

Publication year - 2020

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofaa486

Subject(s) - medicine , retrospective cohort study , prednisolone , pneumonia , cohort , adjunctive treatment , covid-19 , disease , infectious disease (medical specialty)

This is a retrospective cohort study of hospitalized adults with coronavirus disease 2019 (COVID-19). Fifty-seven patients received treatment alone, and 35 patients received treatment with adjunctive prednisolone. A combination of corticosteroids and antivirals was associated with lower risk of clinical progression and invasive mechanical ventilation or death in early COVID-19 pneumonia.

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