Do I Have HIV or Not? Lack of RNA Detection and the Case for Sensitive DNA Testing | Zendy

Sandra A. Springer | Zendy; Silvina Masciotra | Zendy; Jeffrey A. Johnson | Zendy; Sheldon Campbell | Zendy

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Do I Have HIV or Not? Lack of RNA Detection and the Case for Sensitive DNA Testing

Author(s) -

Sandra A. Springer,

Silvina Masciotra,

Jeffrey A. Johnson,

Sheldon Campbell

Publication year - 2020

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofaa478

Subject(s) - medicine , human immunodeficiency virus (hiv) , antiretroviral therapy , diagnostic test , rna , hiv diagnosis , virology , intensive care medicine , viral load , pediatrics , genetics , biology , gene

We present a case of a 20-year-old male who had ambiguous HIV test results after entering new provider care and whose status was later complicated by undetectable viral RNA off antiretroviral therapy (ART). Verifying HIV infection status may occasionally require sensitive DNA testing that might need to be considered in diagnostic guidelines to resolve diagnosis and ensure appropriate ART management.

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