889. Improving patient compliance with preoperative universal decolonization to reduce surgical infection rate and costs

Background In order to address spine patient non-compliance with preoperative nasal decolonization, a trial was undertaken to replace nasal povidone iodine (PVI) with alcohol based nasal antiseptic paired with chlorhexidine (CHG) bathing for all spine fusion and laminectomy patients for a period of three months. Methods In addition to preoperative CHG bathing already in place, an alcohol based nasal antiseptic was applied to the nose of all spine surgery fusion and laminectomy patients within one hour of surgery instead of the PVI nasal antiseptic that had been in use previously. Results After switching the alcohol based nasal antiseptic, there was a reduction in surgical site infections (SSI) of 64% from 0.58 to 0.21/100 spine fusion procedures and a reduction in SSI of 100% from 0.46 to 0.00/100 laminectomy procedures. This represents an estimated cost avoidance of $127K associated with infections prevented. There was also a $37K cost savings resulting from switching from nasal PVI to alcohol based nasal antiseptic, with patients reporting greater satisfaction. Conclusion Universal preoperative decolonization for spine fusion and laminectomy patients using an alcohol based nasal antiseptic and CHG bathing resulted in reduced infection rates and associated costs, reduced nasal antiseptic cost and improved patient satisfaction. Disclosures All Authors: No reported disclosures