What Is the Predictive Value of a Single Nasopharyngeal SARS-CoV-2 PCR Swab Test in a Patient With COVID-Like Symptoms and/or Significant COVID-19 Exposure?
Author(s) -
Blessen George,
James P. McGee,
Eileen Giangrasso,
Sheila Finkelstein,
Susan Wu,
Aaron E. Glatt
Publication year - 2020
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofaa399
Subject(s) - medicine , covid-19 , predictive value , pcr test , virology , titer , polymerase chain reaction , predictive value of tests , real time polymerase chain reaction , betacoronavirus , coronavirus , immunology , virus , biology , disease , gene , biochemistry , outbreak , infectious disease (medical specialty)
Utilizing results of polymerase chain reaction (PCR) testing and subsequent antibody titers, we report on the test characteristics of a PCR screening test for severe acute respiratory syndrome coronavirus 2 among hospital workers. The PCR test was found to be 87% sensitive and 97% specific, with a positive predictive value of 0.98 and a negative predictive value of 0.80.
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