Adverse Events and Healthcare Utilization Associated With Outpatient Parenteral Antimicrobial Therapy Among Older Versus Younger Adults | Zendy

Kaylen Brzozowski | Zendy; Rupak Datta | Zendy; Joseph Canterino | Zendy; Maricar Malinis | Zendy; Manisha JuthaniMehta | Zendy

Open Access

Adverse Events and Healthcare Utilization Associated With Outpatient Parenteral Antimicrobial Therapy Among Older Versus Younger Adults

Author(s) -

Kaylen Brzozowski,

Rupak Datta,

Joseph Canterino,

Maricar Malinis,

Manisha JuthaniMehta

Publication year - 2020

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofaa358

Subject(s) - medicine , odds ratio , confidence interval , adverse effect , antimicrobial , incidence (geometry) , vancomycin , rate ratio , pediatrics , emergency medicine , staphylococcus aureus , chemistry , physics , organic chemistry , biology , bacteria , optics , genetics

Among older (n = 204) versus younger (n = 253) adults, there was no difference in adverse events (adjusted odds ratio [aOR] = 0.98; 95% confidence interval [CI] = 0.6–1.6) or healthcare utilization (incidence rate ratio = 1.09; 95% CI = 0.9–1.3) within 30 days after discontinuing outpatient parenteral antimicrobial therapy. Vancomycin (aOR = 1.92) and oxacillin (aOR = 3.12) were independently associated with adverse events.

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