Nonquinolone Options for the Treatment of Mycoplasma genitalium in the Era of Increased Resistance
Author(s) -
Michelle Doyle,
Lenka A. Vodstrcil,
Erica L. Plummer,
Ivette Aguirre,
Christopher K. Fairley,
Catriona S. Bradshaw
Publication year - 2020
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofaa291
Subject(s) - mycoplasma genitalium , medicine , minocycline , doxycycline , quinolone , antimicrobial , mycoplasma , microbiology and biotechnology , azithromycin , antibiotics , gynecology , chlamydia trachomatis , biology
In the era of increasing macrolide- and quinolone-resistant Mycoplasma genitalium (MG), we report the efficacy of 2 nonquinolone antimicrobials in patients with limited treatment options. Pristinamycin + doxycycline cured 75% (95% CI, 64%–85%), and minocycline cured 71% (95% CI, 54%–85%) of cases. These data provide useful estimates to inform clinical practice.
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