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Incidence of Tuberculosis During the First Year of Antiretroviral Treatment in West African HIV-Infected Adults
Author(s) -
Boris Tchakounte Youngui,
Patrick Coffié,
Eugène Messou,
Armel Poda,
L. Fortes Déguévo,
Denise Hawerlander,
Albert Minga,
Éric Balestre,
François Dabis,
Olivier Marcy
Publication year - 2020
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofaa203
Subject(s) - medicine , incidence (geometry) , tuberculosis , poisson regression , antiretroviral treatment , antiretroviral therapy , human immunodeficiency virus (hiv) , body mass index , isoniazid , coinfection , pediatrics , demography , immunology , viral load , environmental health , population , pathology , optics , physics , sociology
We estimated tuberculosis incidence during the first year on antriretroviral therapy without isoniazid-preventive treatment in 6938 West African HIV-infected adults at 3.33 cases per 100 person-years (95% CI, 2.85–3.80). In multivariate Poisson models, sites in Cote d’Ivoire, male gender, low body mass index, low hemoglobin, low CD4 count, and young age were significantly associated with higher incidence.

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