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Data show that C/T could be a valid option in empiric and/or targeted therapy in patients with severe infections caused by ESBL-producing . Clinicians should be aware of the risk of clinical failure with standard-dose C/T therapy in septic patients receiving CRRT.

open forum infectious diseases

Ceftolozane/Tazobactam for Treatment of Severe ESBL-Producing Enterobacterales Infections: A Multicenter Nationwide Clinical Experience (CEFTABUSE II Study)