Hepatitis C Virus (HCV) Clearance After Treatment With Direct-Acting Antivirals in Human Immunodeficiency Virus (HIV)-HCV Coinfection Modulates Systemic Immune Activation and HIV Transcription on Antiretroviral Therapy | Zendy

Yanina Ghiglione | Zendy; María L. Polo | Zendy; Alejandra Urioste | Zendy; Ajantha Rhodes | Zendy; Alejandro Czernikier | Zendy; César Trifone | Zendy; María Florencia Quiroga | Zendy; Alicia Sisto | Zendy; Patricia Patterson | Zendy; Horacio Salomón | Zendy; María José Rolón | Zendy; Sonia Bakkour | Zendy; Sharon R. Lewin | Zendy; Gabriela Turk | Zendy; Natalia Laufer | Zendy

Open Access

Hepatitis C Virus (HCV) Clearance After Treatment With Direct-Acting Antivirals in Human Immunodeficiency Virus (HIV)-HCV Coinfection Modulates Systemic Immune Activation and HIV Transcription on Antiretroviral Therapy

Author(s) -

Yanina Ghiglione,

María L. Polo,

Alejandra Urioste,

Ajantha Rhodes,

Alejandro Czernikier,

César Trifone,

María Florencia Quiroga,

Alicia Sisto,

Patricia Patterson,

Horacio Salomón,

María José Rolón,

Sonia Bakkour,

Sharon R. Lewin,

Gabriela Turk,

Natalia Laufer

Publication year - 2020

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofaa115

Subject(s) - coinfection , virology , hepatitis c virus , immune system , medicine , virus , immunology , population , hepatitis c , environmental health

Elimination of HCV in HIV/HCV-coinfected individuals alters immune function and the transcriptional activity of latently infected cells. This report provides insights into the effects of HCV coinfection in HIV persistence and regards coinfected subjects as a population in which HIV remission might prove to be more challenging.

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