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Lymphocyte Subsets in HIV-Exposed Uninfected Infants: The Impact of Neonatal Postexposure Prophylaxis With Zidovudine
Author(s) -
Beat M Greiter,
Christian R. Kahlert,
Nadia Eberhard,
Leila SultanBeyer,
Christoph Berger,
P Paioni
Publication year - 2020
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofaa108
Subject(s) - zidovudine , medicine , pre exposure prophylaxis , immunology , post exposure prophylaxis , toxicity , cd19 , cd8 , lymphocyte , human immunodeficiency virus (hiv) , lymphocyte subsets , virology , pediatrics , immune system , viral disease , syphilis , men who have sex with men
HIV-exposed, uninfected (HEU) infants receiving neonatal postexposure prophylaxis with zidovudine showed nonsignificant trends of lower CD4 and CD8 T cells as well as CD19 B cells than those who did not, suggesting toxicity that might impact the overall health of HEU children.

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