Lymphocyte Subsets in HIV-Exposed Uninfected Infants: The Impact of Neonatal Postexposure Prophylaxis With Zidovudine
Author(s) -
Beat M Greiter,
Christian R. Kahlert,
Nadia Eberhard,
Leila SultanBeyer,
Christoph Berger,
P Paioni
Publication year - 2020
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofaa108
Subject(s) - zidovudine , medicine , pre exposure prophylaxis , immunology , post exposure prophylaxis , toxicity , cd19 , cd8 , lymphocyte , human immunodeficiency virus (hiv) , lymphocyte subsets , virology , pediatrics , immune system , viral disease , syphilis , men who have sex with men
HIV-exposed, uninfected (HEU) infants receiving neonatal postexposure prophylaxis with zidovudine showed nonsignificant trends of lower CD4 and CD8 T cells as well as CD19 B cells than those who did not, suggesting toxicity that might impact the overall health of HEU children.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom