Progress and perspectives in plant sterol and plant stanol research | Zendy

Peter J.H. Jones | Zendy; Maryam Shamloo | Zendy; Dylan MacKay | Zendy; Todd C. Rideout | Zendy; Semone B. Myrie | Zendy; Jogchum Plat | Zendy; JeanBaptiste Roullet | Zendy; David J. Baer | Zendy; Kara L. Calkins | Zendy; Harry R. Davis | Zendy; P. Barton Duell | Zendy; Henry N. Ginsberg | Zendy; Helena Gylling | Zendy; David J.A. Jenkins | Zendy; Dieter Lütjohann | Zendy; Mohammad Moghadasian | Zendy; Robert A. Moreau | Zendy; David Mymin | Zendy; Richard E. Ostlund | Zendy; Rouyanne T. Ras | Zendy; Javier Ochoa Reparaz | Zendy; Elke A. Trautwein | Zendy; Stephen D. Turley | Zendy; Tim Vanmierlo | Zendy; Oliver Weingärtner | Zendy

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Progress and perspectives in plant sterol and plant stanol research

Author(s) -

Peter J.H. Jones,

Maryam Shamloo,

Dylan MacKay,

Todd C. Rideout,

Semone B. Myrie,

Jogchum Plat,

JeanBaptiste Roullet,

David J. Baer,

Kara L. Calkins,

Harry R. Davis,

P. Barton Duell,

Henry N. Ginsberg,

Helena Gylling,

David J.A. Jenkins,

Dieter Lütjohann,

Mohammad Moghadasian,

Robert A. Moreau,

David Mymin,

Richard E. Ostlund,

Rouyanne T. Ras,

Javier Ochoa Reparaz,

Elke A. Trautwein,

Stephen D. Turley,

Tim Vanmierlo,

Oliver Weingärtner

Publication year - 2018

Publication title -

nutrition reviews

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.958

H-Index - 150

eISSN - 1753-4887

pISSN - 0029-6643

DOI - 10.1093/nutrit/nuy032

Subject(s) - plant sterols , cholesterol , sterol , biology , phytosterol , disease , medicine , food science , endocrinology

Current evidence indicates that foods with added plant sterols or stanols can lower serum levels of low-density lipoprotein cholesterol. This review summarizes the recent findings and deliberations of 31 experts in the field who participated in a scientific meeting in Winnipeg, Canada, on the health effects of plant sterols and stanols. Participants discussed issues including, but not limited to, the health benefits of plant sterols and stanols beyond cholesterol lowering, the role of plant sterols and stanols as adjuncts to diet and drugs, and the challenges involved in measuring plant sterols and stanols in biological samples. Variations in interindividual responses to plant sterols and stanols, as well as the personalization of lipid-lowering therapies, were addressed. Finally, the clinical aspects and treatment of sitosterolemia were reviewed. Although plant sterols and stanols continue to offer an efficacious and convenient dietary approach to cholesterol management, long-term clinical trials investigating the endpoints of cardiovascular disease are still lacking.

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