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CHRNA5 Variant Predicts Smoking Cessation in Patients With Acute Myocardial Infarction
Author(s) -
LiShiun Chen,
Richard G. Bach,
Petra Lenzini,
John A. Spertus,
Laura J. Bierut,
Sharon Cresci
Publication year - 2014
Publication title -
nicotine and tobacco research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.338
H-Index - 113
eISSN - 1469-994X
pISSN - 1462-2203
DOI - 10.1093/ntr/ntu059
Subject(s) - smoking cessation , medicine , myocardial infarction , pathology
While smoking is a major modifiable risk factor for secondary prevention of myocardial infarction (MI), active smoking is common among patients hospitalized with acute MI. Recent studies suggest that nicotinic receptor variants, and specifically the high-risk CHRNA5 rs16969968 A allele, are associated with cessation failure among noncardiac patients. This study investigates the association between CHRNA5 rs16969968 and smoking cessation in patients hospitalized with acute MI.

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